Groundwater pressure poses a major threat to the stability of underground structures. This study presents a coupled seepage–stress finite element model to investigate...
How does the gut microbiota influence the immune system beyond the production of microbial metabolites? This review highlights an emerging regulatory axis linking...
Biorefineries are an important pathway for the sustainable valorization of biomass, especially in rural and resource-distributed regions. However, their economic...
The 2026 Academic Annual Meeting on Integrative Medicine, Andrology and Sexual Medicine was held in Shanghai on October 24–25, 2026. Under the theme “Integrating Chinese and Western Medicine:...
Guangzhou, China – September 2026 – Dr. Dany Xiang, Head of the Biomedical Journals Department at Tech Science Press (TSP), delivered a seminar on scholarly publishing and manuscript submission...
Accumulating evidence suggests that the gut microbiota regulates cytokine gene expression through multiple epigenetic mechanisms that shape chromatin...
Short-chain fatty acids (SCFAs) are increasingly recognized as active modulators of tumor immunity. However, organizing evidence only by tumor type, metabolite...
Interleukin-18 (IL-18) is a pleiotropic IL-1-family cytokine whose clinical relevance depends strongly on context. A central reason is that IL-18 activity...
Brain tumor localization in magnetic resonance imaging remains challenging for small, low-contrast lesions. This study presents Small Brain Lesion Deep...
Brain tumor detection from magnetic resonance imaging (MRI) is an important task for supporting early diagnosis and treatment planning. However, accurate...
Evaluating objectives and constraints in complex dynamical or multi-physics systems can take minutes to hours per design point, which motivates the use...
Computed tomography (CT) is an essential medical imaging technique that produces high-resolution cross-sectional images, but delivers substantial radiation...
The prevailing capitalist emphasis on perpetual economic growth conflicts with the ecological reality of a planet with finite resources, calling into...
To tackle the challenges of economic operation and low-carbon transition faced by integrated multi-energy systems (IMES) in the energy transition, this...
Autonomous mobile robots increasingly rely on three tightly coupled capabilities: low-latency wireless connectivity, edge-side compute acceleration, and...
Hot-section nickel-based single-crystal superalloy components under isothermal cyclic loading often exhibit systematic life shifts when datasets span...
Cold-start alloy-design campaigns often have too few labeled compositions to reliably locate phase boundaries for tree-structured composition-space Gaussian...
The growing need for intelligent, information-based, and automated transportation systems has been brought about by the rapid progress of intelligent...
Hail impacts on photovoltaic laminates generate strongly nonlinear contact forces whose polynomial restoring form and coefficients govern the resulting...
With the growing world population and demand for agricultural goods, agriculture requires innovative technologies that make the best use of resource,...
Gastric cancer (GC) remains a leading cause of global cancer mortality, with progression and therapy resistance heavily influenced by the dynamic tumor...
The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...
Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...
The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
Welcome to the Special Issue on "Modeling and Applications of Bubbles and Droplets in Engineering and Sciences". This fascinating field...
The tumor microenvironment (TME) plays a crucial role in cancer progression, metastasis, and resistance to therapy, prompting a shift in focus from targeting...
Tumor biomarkers have become an essential foundation for advancements in cancer diagnosis, prognosis, and targeted therapy. As oncology moves towards...
Artificial Intelligence of Things (AIoT) is considered a collaborative application of artificial intelligence (AI) and the Internet of Things (IoT). The...
Accumulating evidence suggests that the gut microbiota regulates cytokine gene expression through multiple epigenetic mechanisms that shape chromatin...
Short-chain fatty acids (SCFAs) are increasingly recognized as active modulators of tumor immunity. However, organizing evidence only by tumor type, metabolite...
Interleukin-18 (IL-18) is a pleiotropic IL-1-family cytokine whose clinical relevance depends strongly on context. A central reason is that IL-18 activity...
Brain tumor localization in magnetic resonance imaging remains challenging for small, low-contrast lesions. This study presents Small Brain Lesion Deep...
Brain tumor detection from magnetic resonance imaging (MRI) is an important task for supporting early diagnosis and treatment planning. However, accurate...
Evaluating objectives and constraints in complex dynamical or multi-physics systems can take minutes to hours per design point, which motivates the use...
Computed tomography (CT) is an essential medical imaging technique that produces high-resolution cross-sectional images, but delivers substantial radiation...
The prevailing capitalist emphasis on perpetual economic growth conflicts with the ecological reality of a planet with finite resources, calling into...
To tackle the challenges of economic operation and low-carbon transition faced by integrated multi-energy systems (IMES) in the energy transition, this...
Autonomous mobile robots increasingly rely on three tightly coupled capabilities: low-latency wireless connectivity, edge-side compute acceleration, and...
Hot-section nickel-based single-crystal superalloy components under isothermal cyclic loading often exhibit systematic life shifts when datasets span...
Cold-start alloy-design campaigns often have too few labeled compositions to reliably locate phase boundaries for tree-structured composition-space Gaussian...
The growing need for intelligent, information-based, and automated transportation systems has been brought about by the rapid progress of intelligent...
Hail impacts on photovoltaic laminates generate strongly nonlinear contact forces whose polynomial restoring form and coefficients govern the resulting...
With the growing world population and demand for agricultural goods, agriculture requires innovative technologies that make the best use of resource,...
Gastric cancer (GC) remains a leading cause of global cancer mortality, with progression and therapy resistance heavily influenced by the dynamic tumor...
The rapid evolution of chemical biology, medicinal chemistry, and molecular pharmacology continues to drive the discovery of innovative anticancer compounds...
Cancer development and therapeutic response are governed not only by genetic alterations but also by dynamic regulatory mechanisms at the epigenetic and...
The transition toward decentralized smart grids is reshaping the way energy is generated, exchanged, controlled, and consumed. The increasing penetration...
Cancer remains one of the leading causes of morbidity and mortality worldwide, and its onset and progression are closely linked to dysregulated epigenetic...
Welcome to the Special Issue on "Modeling and Applications of Bubbles and Droplets in Engineering and Sciences". This fascinating field...
The tumor microenvironment (TME) plays a crucial role in cancer progression, metastasis, and resistance to therapy, prompting a shift in focus from targeting...
Tumor biomarkers have become an essential foundation for advancements in cancer diagnosis, prognosis, and targeted therapy. As oncology moves towards...
Artificial Intelligence of Things (AIoT) is considered a collaborative application of artificial intelligence (AI) and the Internet of Things (IoT). The...
Background: The mental health challenges facing scientific and technological researchers, together with increasing demands for innovation performance, underscore the importance of research resilience, which helps protect mental health and sustain innovation performance. Accordingly, drawing on conservation of resources theory, social cognitive theory, and cognitive appraisal theory, this study investigated how perceived innovation environment may contribute to research resilience through the two candidate indirect pathways of research self-efficacy and anxiety and examined the moderating role of perceived…
Background: Older adults with functional disability are particularly vulnerable to poor oral health and psychological distress, yet the role of oral health-related quality of life in linking these conditions remains insufficiently understood. This study assessed oral health status, OHRQoL, and psychological distress among community-dwelling older adults with functional disability and examined whether OHRQoL was statistically associated with an indirect pathway between oral health status and psychological distress. Methods: A cross-sectional study was conducted involving 168 older…
Background: Parental phubbing has become increasingly prevalent in the digital age and has been associated with adolescents’ maladjustment. However, less is known about the relational processes through which parental phubbing is associated with academic burnout, particularly among Chinese older adolescents. This study aimed to examine whether alienation was associated with the relationship between parental phubbing and academic burnout and whether perceived social support from different sources moderated these associations. Methods: A cross-sectional survey was conducted among…
Background: University students and staff experience elevated levels of psychological distress, highlighting the need for accessible interventions that promote well-being, emotional regulation, and resilience within higher education settings. This study aims to evaluate the effectiveness of the GestEm-U hybrid intervention in enhancing psychological well-being, mindfulness-related facets, and reducing psychopathological symptoms among university students and staff. Specifically, the research examines the impact of integrating mindfulness with values-based action and emotional regulation and observes how these internal shifts…
Background: Physical and occupational therapy students face academic and clinical stressors, but longitudinal changes in anxiety and its association with self-efficacy remain unclear. This study examined state anxiety across curriculum-based educational stages, including clinical practicum, and its association with self-efficacy in a Japanese cohort. Methods: This 3-year longitudinal observational study included 144 physical and occupational therapy students at one Japanese university. State anxiety (State-Trait Anxiety Inventory–Form JYZ) and General Self-Efficacy Scale (GSES) were assessed at six…
Background: Problematic digital use has been strongly associated with psychological disturbance, but it is less researched among highly distressed populations such as prenatal mothers. The present study longitudinally explored the predictors of problematic smartphone use (PSPU) and problematic social media use (PSMU) among prenatal mothers to inform the development of preventive strategies. Methods: Participants comprised 137 prenatal mothers (mean age = 31.89 years, SD = 4.29), with approximately half of them having their first baby (50.4%).…
Background: An increase in the prevalence of mental illness among Indian university students has led to educational policies that make mental health education and services compulsory in educational settings. However, students’ perceptions of the effectiveness and role of these resources in meeting their mental health needs have not been sufficiently explored. The study used a qualitative exploratory design to understand participants’ perceptions of services and mental health education offered by their institutions. Methods: Data was collected…
Background: While oral diseases are the most prevalent noncommunicable conditions in older adults and are associated with poorer cognitive outcomes, the psychosocial mechanisms mediating this association remain unclear. This study aimed to examine whether life satisfaction mediates the relationship between self-rated oral health and cognitive function of older adults. Methods: We conducted a cross-sectional analysis of 1090 participants aged 50 years old or older from the 2018 Health and Retirement Study (HRS). Our cross-sectional study used…
Background: Physical activity is an important contributor to health-related quality of life, while exercise imagery may serve as a cognitive strategy that supports greater engagement in physical activity. Objectives: This study investigated how exercise imagery, physical activity, and the physical and mental components of health-related quality of life are structurally associated among community-dwelling adults. Methods: A total of 571 adults living in Nowon-gu, a district in northern Seoul, South Korea, participated in this study. Exercise imagery was…
Objective: During major public health emergencies, lockdown and home quarantine measures restrict in-person interaction, making online social support an important means of sustaining social connection. Using the COVID-19 pandemic as a representative case of such emergencies, this study explores the content, functions, and influencing factors of online social support, aiming to inform the delivery of targeted psychosocial services. Methods: A qualitative study was conducted with semi-structured in-depth interviews among 20 young Chinese adults who had experienced…
Background: Health care professionals are exposed to occupational stressors that increase vulnerability to psychological distress and reduced well-being. Interventions grounded in positive mental health models may strengthen protective psychological resources in workplace settings. Methods: This quasi-experimental, single-group study examined changes associated with participation in the “Mais Por Ti” Positive Mental Health Promotion Program among health care professionals in an urban Portuguese health unit. Participants were assessed at baseline (T1), immediately post-intervention (T2), and six months later…
Background: Attention deficit/Hyperactivity disorder (ADHD) is frequently associated with executive functions (EF) impairments (working memory, inhibitory control, planning, attention, and cognitive flexibility), underlying self-regulation, learning, and academic problems. In recent years, computerised executive function training (CCT) has been proposed as a non-pharmacological intervention tool designed to specifically stimulate EF through adaptive digital tasks. These programs are based on the hypothesis that repeated and progressive training of executive components can produce generalised improvements in cognitive functioning and,…
Oral squamous cell carcinoma (OSCC) remains associated with substantial morbidity and mortality, and only a subset of patients derive durable benefit from immune-checkpoint blockade. Single-cell and spatial approaches reveal cellular states and tissue organization that bulk profiling cannot resolve. These findings suggest that therapeutic responses may depend on both cellular function and the local interactions that sustain it. This narrative review integrates single-cell transcriptomic, spatial, functional and clinical studies of the OSCC microenvironment. We distinguish…
Lipocalin 2 (LCN2) was initially identified as a lipid carrier protein, and recent studies have revealed it acts as a multifunctional regulator of cancer progression that is closely associated with ferroptosis. Ferroptosis is a newly discovered form of programmed cell death, characterized by alterations in intracellular iron content and lipid peroxidation levels, and disruption of antioxidant defense systems. Given the close connection between ferroptosis and multiple diseases, particularly cancer, investigation into the mechanisms underlying ferroptosis…
Numerous solid tumours have bone as one of their most common sites of distant metastasis, and bone metastasis causes skeletal-related events (SREs) that impair quality of life and portend poor prognosis. Bone metastasis arises not from invasive tumour cells alone but through mutual adaptation and co-evolution between tumour cells and the bone microenvironment. A key mechanism of immune evasion is the establishment of an immunosuppressive microenvironment, wherein tumour-derived cytokines, metabolic reprogramming, and extracellular vesicles drive…
Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is associated with aggressive disease and poor prognosis. Despite advances in HER2-targeted therapies, resistance remains a major clinical challenge. This review focuses on the mechanisms of resistance to HER2-targeted therapies, with particular emphasis on the tumor microenvironment (TME). The TME, composed of immune cells, cancer-associated fibroblasts (CAFs), and extracellular matrix components, significantly influences therapeutic responses. Immunosuppressive cells such as tumor-associated macrophages (TAMs), regulatory T cells (Tregs),…
Guest Editors: Van-Tu Nguyen; Ould el Moctar; Anh Dinh Le; Hemant J. Sagar Deadline: 30 September 2027
Guest Editors: Jin-Gyun Kim; Hee-Sun Choi; Seongji Han Deadline: 30 September 2027
Guest Editors: Shaoyi Zhang Deadline: 31 July 2027
Guest Editors: Giribabu Nelli Deadline: 30 June 2027
Guest Editors: Mauro Cappelli; Stefano di Gennaro Deadline: 31 May 2027
Guest Editors: Rosa Rodriguez Deadline: 31 May 2027
Guest Editors: Hung-Yu Lin; Hsing-Ju Wu Deadline: 31 May 2027
Guest Editors: Carlos Vargas-Salgado; Dácil Diaz-Bello Deadline: 30 April 2027
Guest Editors: Leonardo Di G. Sigalotti; Carlos A. Vargas; Carlos E. Alvarado-Rodríguez Deadline: 30 April 2027
Guest Editors: Sabrina Tosi; Annabelle Lewis Deadline: 30 April 2027
Guest Editors: Antonella Petrillo; Fabio De Felice Deadline: 15 April 2027
Guest Editors: Wenlong Sun; Mengyao Li Deadline: 31 March 2027
Guest Editors: Divya Gopinath; Qi Wang; Hengrui Liu; Zhirui Zeng Deadline: 31 March 2027
Guest Editors: Wenbing Zhao; Pan Wang Deadline: 31 March 2027
Guest Editors: Wenfeng Zheng; Choon Kit Chan; Kyungtae Kang; Chao Liu Deadline: 31 March 2027
Guest Editors: Chunguang Guo; Zaoqu Liu; Jialin Meng Deadline: 31 March 2027






